MOTS-c Metabolic Research: Mitochondrial Signalling and Current Evidence

Researchers increasingly recognize mitochondria as more than cellular energy producers. They also participate in biological signalling, including through small peptides encoded within mitochondrial DNA. One example is MOTS-c, a mitochondrial-derived peptide investigated for its relationship with energy sensing, glucose metabolism, skeletal muscle, and metabolic stress. Interest in MOTS-c metabolic research has grown because experimental studies […]