Incretin Signalling Research: GLP-1, GIP, and Metabolic Regulation

Incretin signalling research examines how gastrointestinal hormones connect nutrient intake with pancreatic and metabolic responses. Two hormones dominate this field: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Both hormones contribute to glucose-dependent insulin regulation. However, they activate different receptors and differ in glucagon signalling and broader metabolic activity. These distinctions have become particularly important […]